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GLP-3R

Price range: $153.60 through $403.20

Lyophilized powder - research reference material

This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.

Quality Certificates

Independent third-party lab analysis (CoA) - from our own in-house brand.

Not available in USA.

GLP-3R - Triple GLP-1/GIP/GCGR Receptor Agonist Peptide, Research Reference Material

FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.

2D chemical structure of GLP-3R - Triple GLP-1/GIP/GCGR Receptor Agonist Peptide, Research Reference Material
Two-dimensional chemical structure. Depiction for identification only.
Amino-acid sequence of GLP-3R - Triple GLP-1/GIP/GCGR Receptor Agonist Peptide, Research Reference Material
Primary amino-acid sequence, N to C. Tiles colored by side-chain class.

Analytical Identity

Identity & nomenclature
Common nameGLP-3R
Amino-acid sequenceYXQGTFTSDYSILLDKKAQXAFIEYLLEGGPSSGAPPPS (X = Aib)
Sequence (3-letter)Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser
Residues19
CAS Number2381089-83-2
PubChem CID171390338
InChIKeyMLOLQJNKXBNWFW-SAGGEDDASA-N
SMILESCCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NCC(=O)NCC(=O)N2CCCC2C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N3CCCC3C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(CO)C(=O)N)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCCCNC(=O)COCCOCCNC(=O)CCC(C(=O)O)NC(=O)CCCCCCCCCCCCCCCCCCC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(C)(CC(C)C)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC8=CC=CC=C8)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(C)(C)NC(=O)C(CC9=CC=C(C=C9)O)N
Physicochemical
Molecular formulaC221H342N46O68
Molecular weight4731.33 g/mol
Monoisotopic mass4728.4718 Da
AppearanceWhite to off-white lyophilized powder
Physical formLyophilized powder
Quality & provenance
PurityNot less than 98% by HPLC (see lot-specific Certificate of Analysis)
SourceSynthetic
Catalog / SKUGLP-3R

GLP-3R is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. The compound is a synthetic, single-chain lipidated peptide amide catalogued under SKU GLP-3R and CAS 2381089-83-2, with PubChem CID 171390338 and InChIKey MLOLQJNKXBNWFW-SAGGEDDASA-N providing unambiguous cross-referencing across chemical databases.

The molecule is characterized by the empirical formula C221H342N46O68, an average molecular weight of 4731.33 g/mol and a monoisotopic mass of 4728.4718 Da. Its primary structure is defined by the amino-acid sequence YXQGTFTSDYSILLDKKAQXAFIEYLLEGGPSSGAPPPS, where X denotes alpha-aminoisobutyric acid (Aib) substitutions at positions 2 and 20. These two Aib residues are conformationally restricted, non-proteinogenic building blocks that are widely used in peptide chemistry as structural motifs at the N-terminal region and mid-chain of GLP-3R-type analogs. The C-terminal segment is captured in the three-letter descriptor Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser (19 residues), a proline- and serine-rich tail characteristic of extended incretin-family scaffolds.

Consistent with the SMILES string on file, GLP-3R additionally carries a lipid-conjugated lysine side chain, in which a C20 diacid (eicosanedioic acid) is attached through a gamma-glutamate spacer and a mini-PEG (OEG-OEG) linker to the epsilon-amine of an internal lysine. This fatty-diacid/gamma-Glu/PEG2 architecture is a well-known albumin-binding motif in peptide reference chemistry and contributes significantly to the observed high molecular mass of the intact conjugate.

GLP-3R is supplied as a white to off-white lyophilized powder of synthetic origin, with a specified purity of not less than 98% by HPLC. Identity and purity for every batch are documented on the lot-specific Certificate of Analysis, available on request, and the listed molecular formula, exact mass and InChIKey allow analysts to confirm identity by high-resolution mass spectrometry, LC-UV and orthogonal spectroscopic techniques. The lyophilized format is suitable for gravimetric handling and reconstitution under standard peptide-laboratory protocols in appropriate solvent systems chosen by the investigator.

Published scientific literature has examined GLP-3R-class peptides in preclinical, in-vitro receptor-binding and biochemical characterization studies as tool compounds at incretin-family receptors. PEPTIDE.Power provides GLP-3R strictly as an analytical and identity reference standard and makes no therapeutic, diagnostic or efficacy claims regarding this material, and offers no administration or dosing guidance. This material is not a drug, dietary supplement, cosmetic or food, and is not for human or veterinary use, injection, or ingestion.

Physical format

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Certificate of Analysis

Issuing laboratoryInternal LC-MS Lab Results
AnalyteGLP-3R
CAS Number2381089-83-2
Lot / Batch07.2026 / S2
AppearanceWhite to off-white lyophilized powder
Purity (HPLC)99.57%
IdentityConfirmed by HPLC and mass spectrometry

Lot-specific COA available — contact [email protected] with your lot number.

Storage & handling

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

Scientific references

The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.

  1. Triple-hormone-receptor agonist rеtаtrutіdе for obesity — https://pubmed.ncbi.nlm.nih.gov/37366315/
  2. Efficacy and safety of r​еtаtrutіdе, a novel GLP-1, GIP, and glucagon receptor agonist, in adults with obesity: a randomised, placebo-controlled, phase 2 trial — https://pmc.ncbi.nlm.nih.gov/articles/PMC12026077/
  3. R​еtаtrutіdе - a game changer in obesity pharmacotherapy — https://pubmed.ncbi.nlm.nih.gov/40563436/
  4. Unleashing the power of r​еtаtrutіdе: a possible triumph over obesity and its comorbidities — https://pubmed.ncbi.nlm.nih.gov/38323122/
  5. Effects of once-weekly subcutaneous Rr​еtаtrutіdе on weight and metabolic markers in adults with obesity: a randomized phase 2 trial — https://pubmed.ncbi.nlm.nih.gov/39318607/
  6. Effects of rеtаtrutіdе on body composition in people with type 2 diabetes: a post hoc analysis of a randomised, double-blind, placebo-controlled phase 2 trial — https://pubmed.ncbi.nlm.nih.gov/40609566/

Eligibility & terms of sale

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.

FAQ

What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.

What form does it ship in?
A lyophilized powder in a sealed vial.

Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.

Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.

Related reference materials

Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.