HCG (Choriomon)

HCG (Human Chorionic Gonadotropin, CAS 9002-61-3) is supplied by PEPTIDE.Power as a laboratory research reference material intended strictly for in-vitro and laboratory research use. As a member of the glycoprotein hormone family, HCG is a heterodimeric molecule composed of a non-covalently associated alpha subunit and a hormone-specific beta subunit, with the extensively characterized composition summarized by the molecular formula C1105H1770N318O336S26 and an approximate molecular weight of 36,700 g/mol. The relatively high mass reflects the substantial contribution of N- and O-linked oligosaccharide chains attached to the polypeptide backbone, a structural feature that makes HCG a frequent reference point in glycoprotein analytical workflows.

Structurally, the alpha subunit is shared with other pituitary glycoprotein hormones, while the beta subunit confers identity and is distinguished by a carboxyl-terminal peptide extension bearing multiple O-linked glycans. Both subunits are stabilized by intramolecular disulfide bonds, consistent with the 26 sulfur atoms indicated by the molecular formula and reflected in the cystine-knot motif typical of this hormone class. This combination of disulfide-constrained folding and heavy glycosylation is relevant to analysts developing methods for intact-mass determination, subunit dissociation studies, peptide mapping after enzymatic digestion, glycan profiling, and isoform separation by charge-based techniques such as isoelectric focusing or ion-exchange chromatography.

The material is provided as a white to off-white lyophilized powder derived from a synthetic source, presented in a physical form suited to reconstitution in laboratory buffers for bench-scale characterization experiments. Purity is specified as not less than 98% by HPLC, with identity and purity documented on the lot-specific Certificate of Analysis, which is available on request and serves as the sole authoritative record of lot-specific analytical values. Researchers using HCG as a comparator or system-suitability standard will typically confirm identity by orthogonal techniques such as SDS-PAGE under reducing and non-reducing conditions, size-exclusion chromatography, reversed-phase HPLC, and mass spectrometry, taking care to account for glycoform heterogeneity when interpreting mass envelopes.

Published scientific literature has examined HCG across a range of preclinical and analytical contexts, and this catalog entry (SKU: HCG) is intended to support that type of characterization, method development, and reference-standard work. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance of any kind. This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion; it is offered exclusively as a laboratory reference substance for qualified research personnel operating under appropriate institutional controls.

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.