Tesamorelin
Price range: $140.99 through $208.99
This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.
Quality Certificates
Independent third-party lab analysis (CoA) - from our own in-house brand.
Tesamorelin - Synthetic GHRH Analog, Research Reference Material
Analytical Identity
| Common name | Tesamorelin |
|---|---|
| Amino-acid sequence | Tyr-DAla-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 |
| CAS Number | 218949-48-5 |
| PubChem CID | 16137828 |
| InChIKey | QBEPNUQJQWDYKU-BMGKTWPMSA-N |
| SMILES | CCC=CCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)N |
| Molecular formula | C221H366N72O67S |
|---|---|
| Molecular weight | 5135.87 g/mol |
| Monoisotopic mass | 5132.7166 Da |
| Appearance | White to off-white lyophilized powder |
| Physical form | Lyophilized powder |
| Purity | Not less than 98% by HPLC (see lot-specific Certificate of Analysis) |
|---|---|
| Source | Synthetic |
| Catalog / SKU | Tesamorelin |
Tesamorelin is offered strictly as a laboratory research reference material for in-vitro and laboratory research use only. It is a fully synthetic 44-residue peptide amide corresponding to a growth hormone-releasing hormone (GHRH) analog scaffold, distinguished from the native GHRH(1-44) sequence by an N-terminal trans-3-hexenoyl acylation on the tyrosine alpha-amino group. This lipophilic modification, together with the D-alanine substitution at position 2, is the structural feature that defines Tesamorelin as a discrete chemical entity within the GHRH analog family and is a common point of interest in analytical method development and stability profiling.
The material is characterized by molecular formula C221H366N72O67S, average molecular weight 5135.87 g/mol, and a monoisotopic mass of 5132.7166 Da, indexed under CAS 218949-48-5, PubChem CID 16137828, and InChIKey QBEPNUQJQWDYKU-BMGKTWPMSA-N. The complete primary structure is Tyr-DAla-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2, terminating in a C-terminal carboxamide. Notable side-chain features relevant to analytical handling include four arginine residues, two lysines, a single methionine (a potential oxidation-sensitive site), multiple aspartate and glutamate residues that can influence isoelectric behavior, and asparagine positions that are common considerations in deamidation studies.
Tesamorelin is supplied as a white to off-white lyophilized powder from a synthetic source, with purity established at not less than 98% by HPLC and confirmed on a lot-specific Certificate of Analysis. Identity is typically corroborated by orthogonal techniques such as reversed-phase HPLC retention profiling, high-resolution ESI or MALDI mass spectrometry against the monoisotopic mass, and amino-acid or sequence analysis; the SMILES string provided with each lot supports cheminformatics workflows and structure-based database matching.
Published scientific literature has examined Tesamorelin in preclinical research, and the compound serves investigators as a well-defined GHRH-analog reference standard for comparative characterization, chromatographic system suitability, mass-spectrometric identity confirmation, and peptide stability or degradation-pathway studies. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance.
This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. Identity and purity are documented on the lot-specific Certificate of Analysis, available on request.
Physical format
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.
Certificate of Analysis
| Issuing laboratory | Analiza Białek |
|---|---|
| Analyte | Tesamorelin |
| CAS Number | 218949-48-5 |
| Lot / Batch | K12PP |
| Appearance | White to off-white lyophilized powder |
| Purity (HPLC) | 99% |
| Identity | Confirmed by HPLC and mass spectrometry |
Lot-specific COA available — contact [email protected] with your lot number.
Storage & handling
Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.
Scientific references
The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.
- Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data — https://pubmed.ncbi.nlm.nih.gov/20554713/
- The growth hormone releasing hormone analogue, tesamorelin, decreases muscle fat and increases muscle area in adults with HIV — https://pmc.ncbi.nlm.nih.gov/articles/PMC6766405/
- Effects of tesamorelin on nonalcoholic fatty liver disease in HIV: a randomized, double-blind, multicenter trial — https://pmc.ncbi.nlm.nih.gov/articles/PMC6981288/
- Tesamorelin improves fat quality independent of changes in fat quantity — https://pmc.ncbi.nlm.nih.gov/articles/PMC8243807/
- Tesamorelin, a human growth hormone releasing factor analogue — https://pubmed.ncbi.nlm.nih.gov/19243281/
- Growth hormone and tesamorelin in the management of HIV disease — https://pmc.ncbi.nlm.nih.gov/articles/PMC3218714/
Eligibility & terms of sale
This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.
FAQ
What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.
What form does it ship in?
A lyophilized powder in a sealed vial.
Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.
Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.
Related reference materials
Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.
