PT-141 (Bremelanotide)

PT-141 is supplied as a laboratory research reference material intended for in-vitro and laboratory research use only. It is a synthetic, cyclic heptapeptide analog belonging to the melanocortin-receptor-active peptide family, cataloged under CAS 189691-06-3 and PubChem CID 9941379. The molecule is defined by the amino-acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH, in which an N-terminal acetyl-norleucine residue is followed by a lactam macrocycle formed between the side chains of the aspartate and lysine residues, incorporating His, D-Phe, Arg and Trp within the ring.

Analytically, PT-141 carries the molecular formula C50H68N14O10 with an average molecular weight of 1025.2 g/mol and a monoisotopic mass of 1024.5243 Da, providing a well-defined target ion for high-resolution mass spectrometric confirmation of identity. Its canonical SMILES is CCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)O)NC(=O)C, and the standard InChIKey FFHBJDQSGDNCIV-MFVUMRCOSA-N supports unambiguous cross-referencing across chemical databases. The presence of a guanidino group (Arg), an imidazole (His), an indole (Trp), a free carboxylate and multiple amide bonds contributes to a zwitterionic, hydrogen-bond-rich character typical of macrocyclic melanocortin-receptor-agonist peptides used as reference standards.

The material is produced by chemical synthesis and provided as a white to off-white lyophilized powder with a documented purity of not less than 98% by HPLC. Each lot is accompanied by a Certificate of Analysis available on request, which reports identity confirmation (typically by ESI-MS against the expected monoisotopic mass) and chromatographic purity, allowing analysts and formulation chemists to use PT-141 as a comparator for retention-time matching, calibration curves, method development, impurity profiling and structural characterization workflows.

Published scientific literature has examined PT-141 in preclinical research contexts, and this listing is provided strictly for informational and analytical reference purposes. PEPTIDE.Power makes no therapeutic, diagnostic or efficacy claims regarding this material and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic or food, and is not for human or veterinary use, injection or ingestion; it is intended solely as a laboratory reference substance handled by qualified personnel under appropriate research controls.

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.