MGF
$74.99
This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.
Quality Certificates
Independent third-party lab analysis (CoA) - from our own in-house brand.
MGF - IGF-1 Splice Variant Peptide, Research Reference Material
Analytical Identity
| Common name | MGF |
|---|---|
| Amino-acid sequence | YQPPSTNKNTKSQRRKGSTFEERK |
| Sequence (3-letter) | Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys |
| Residues | 24 |
| CAS Number | 12656-61-4 |
| Molecular formula | C121H200N42O39 |
|---|---|
| Molecular weight | ~2868 g/mol |
| Appearance | White to off-white lyophilized powder |
| Physical form | Lyophilized powder |
| Purity | Not less than 98% by HPLC (see lot-specific Certificate of Analysis) |
|---|---|
| Source | Synthetic |
| Catalog / SKU | MGF |
MGF (Mechano Growth Factor) is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. This synthetic 24-residue peptide corresponds to a splice variant of the IGF-1 gene and is offered under catalog SKU MGF, CAS 12656-61-4, with the amino-acid sequence YQPPSTNKNTKSQRRKGSTFEERK (Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys).
The primary structure combines two proline residues near the N-terminus with a basic core rich in lysine and arginine (contributing to an overall net-positive charge at neutral pH) and a short acidic Glu-Glu segment toward the C-terminus. This distribution of polar, charged and hydroxyl-bearing side chains (multiple Ser, Thr and Lys residues) gives MGF good aqueous handling characteristics and makes it a useful reference standard for reversed-phase HPLC, mass spectrometry, and ion-exchange method development. Analytically, MGF is characterized by molecular formula C121H200N42O39 and a monoisotopic-consistent average molecular weight of approximately 2868 g/mol.
The material is manufactured by solid-phase peptide synthesis (source: synthetic; no animal-derived starting materials) and supplied as a white to off-white lyophilized powder. Purity is specified at not less than 98% by HPLC, with residual counter-ion, water content and identity confirmation reported on the lot-specific Certificate of Analysis available on request. For formulator and analytical workflows, MGF is well suited as an identity marker, retention-time reference, and comparator peptide alongside related IGF-1 family sequences.
Published scientific literature has examined MGF in preclinical and in-vitro research contexts; PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. It is distributed exclusively to qualified researchers and institutions for laboratory reference and characterization work.
Physical format
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.
Certificate of Analysis
| Issuing laboratory | Analiza Białek |
|---|---|
| Analyte | MGF |
| CAS Number | 12656-61-4 |
| Lot / Batch | K12PP |
| Appearance | White to off-white lyophilized powder |
| Purity (HPLC) | 99% |
| Identity | Confirmed by HPLC and mass spectrometry |
Lot-specific COA available — contact [email protected] with your lot number.
Storage & handling
Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.
Scientific references
The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.
- Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration — https://pubmed.ncbi.nlm.nih.gov/12433942/
- The expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise — https://pmc.ncbi.nlm.nih.gov/articles/PMC2278043/
- Mechano-growth factor stimulates proliferation and inhibits differentiation of skeletal muscle satellite cells — https://pubmed.ncbi.nlm.nih.gov/14625211/
- Mechano growth factor E peptide induces the increase of protein synthesis via PI3K-Akt-mTOR pathway — https://pmc.ncbi.nlm.nih.gov/articles/PMC2278957/
- Differential splicing of the IGF-I gene to yield forms that are essential for muscle repair — https://pubmed.ncbi.nlm.nih.gov/15860415/
- Mechano-growth factor, an IGF-I splice variant, rescues motoneurons and improves muscle function in models of neurodegeneration — https://pmc.ncbi.nlm.nih.gov/articles/PMC4060426/
Eligibility & terms of sale
This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.
FAQ
What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.
What form does it ship in?
A lyophilized powder in a sealed vial.
Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.
Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.
Related reference materials
Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.
