Cortagen

Cortagen is supplied strictly as a laboratory research reference material intended for in-vitro and laboratory research use only. The item is a short synthetic tetrapeptide corresponding to the sequence Ala-Glu-Asp-Pro (single-letter AEDP), assembled from four residues with a free N-terminal alanine and a C-terminal proline. It carries CAS registry number 196604-48-5, molecular formula C17H26N4O9, and a monoisotopic-consistent average molecular weight of 430.41 g/mol, providing an unambiguous identity handle for cross-referencing in analytical workflows.

Structurally, Cortagen combines one nonpolar residue (Ala), two acidic residues bearing free side-chain carboxylates (Glu and Asp), and a secondary-amine cyclic imino acid at the C-terminus (Pro). The resulting molecule is anionic at neutral pH, water-soluble, and lacks aromatic chromophores, so UV detection is typically performed at low wavelengths (peptide-bond absorbance near 210-220 nm) rather than at 280 nm. The proline residue restricts backbone rotation and can influence chromatographic retention and mass-spectrometric fragmentation patterns useful for confirmatory identification.

The material is offered as a synthetic, lyophilized white to off-white powder (SKU: CORTAGEN), produced by chemical synthesis rather than from biological extraction. Purity is specified as not less than 98% by HPLC, with lot-specific identity, purity, counterion, and residual-solvent data documented on the Certificate of Analysis available on request. Typical release characterization on reference peptides of this class includes reversed-phase HPLC for chromatographic purity, ESI or MALDI mass spectrometry for molecular-weight confirmation against the theoretical 430.41 g/mol, and amino-acid or sequence verification where required by the receiving laboratory.

For handling in a research setting, formulators generally store lyophilized Cortagen sealed, desiccated, and protected from light and humidity; short peptides containing Asp-Pro linkages are known in the literature to be sensitive to acidic hydrolysis, so working solutions are commonly prepared in buffered aqueous systems and aliquoted to minimize freeze-thaw cycles. These are general analytical-chemistry considerations for reference-standard management and are not administration instructions.

Published scientific literature has examined Cortagen in preclinical, non-clinical research contexts, and its compact acidic tetrapeptide structure makes it a convenient reference item for method development, assay calibration, chromatographic system-suitability work, and comparative peptide characterization studies. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance of any kind.

This product is not a drug, dietary supplement, cosmetic, or food. It is not intended for human or veterinary use, and is not for injection, ingestion, topical application, or any form of in-vivo administration. Distribution is limited to qualified researchers and institutions operating under appropriate laboratory controls.

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.