HEP-1
$87.99
This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.
HEP-1 - Synthetic 14-Residue Ezrin-Derived Peptide, Research Reference Material
Analytical Identity
| Common name | HEP-1 |
|---|---|
| Amino-acid sequence | TEKKRRETVEREKE |
| Sequence (3-letter) | Thr-Glu-Lys-Lys-Arg-Arg-Glu-Thr-Val-Glu-Arg-Glu-Lys-Glu |
| Residues | 14 |
| CAS Number | 174641-44-2 |
| PubChem CID | 25078222 |
| Molecular formula | C74H132N26O27 |
|---|---|
| Molecular weight | ~1818.0 g/mol |
| Monoisotopic mass | 1816.976 Da |
| Appearance | White to off-white lyophilized powder |
| Physical form | Lyophilized powder |
| Purity | Not less than 98% by HPLC (see lot-specific Certificate of Analysis) |
|---|---|
| Source | Synthetic |
| Catalog / SKU | HEP-1 |
HEP-1 (catalog HEP-1) is supplied as a synthetic linear 14-residue peptide reference material in the form of a white to off-white lyophilized powder. The sequence (one-letter) is TEKKRRETVEREKE, or Thr-Glu-Lys-Lys-Arg-Arg-Glu-Thr-Val-Glu-Arg-Glu-Lys-Glu in three-letter notation, corresponding to human ezrin residues 324-337 (human ezrin peptide 1). It is intended strictly as a laboratory reference item for analytical and characterization work.
Analytical identifiers include molecular formula C74H132N26O27, average molecular weight ~1818.0 g/mol, monoisotopic mass 1816.976 Da and expected [M+H]+ at 1817.983, with CAS 174641-44-2 and PubChem CID 25078222. The composition (5 Glu, 3 Lys, 3 Arg, 2 Thr, 1 Val) is highly charged and strongly hydrophilic, which is relevant to its behaviour in reversed-phase HPLC (short retention on C18 under standard aqueous-acetonitrile gradients with TFA or formic acid modifiers) and in ion-exchange separations. The high basic residue count and defined monoisotopic mass make LC-MS and high-resolution MS straightforward tools for identity confirmation.
Purity is specified as not less than 98% by HPLC, and a lot-specific Certificate of Analysis documenting HPLC purity and mass-spectrometric identity is available on request.
Published cell and animal research literature exists on this peptide sequence and may be consulted by qualified investigators. PEPTIDE.Power makes no therapeutic, diagnostic or efficacy claims and provides no administration guidance; this material is not a drug, supplement, cosmetic or food, is not for human or veterinary use, injection or ingestion, and is offered for qualified researchers only.
Physical format
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.
Certificate of Analysis
| Analyte | HEP-1 |
|---|---|
| CAS Number | 174641-44-2 |
| Appearance | White to off-white lyophilized powder |
| Identity | Confirmed by HPLC and mass spectrometry |
| Expected [M+H]+ | m/z 1817.983 (calculated, monoisotopic) |
Lot-specific COA available — contact [email protected] with your lot number.
Storage & handling
Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.
Scientific references
The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.
- Chulkina MM, Pichugin AV, Ataullakhanov RI. Peptides 2020;132:170364 — https://pubmed.ncbi.nlm.nih.gov/32621844/
- Synthetic peptide TEKKRRETVEREKE derived from ezrin induces differentiation of NIH/3T3 fibroblasts — https://pubmed.ncbi.nlm.nih.gov/28668507/
Eligibility & terms of sale
This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.
FAQ
What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.
What form does it ship in?
A lyophilized powder in a sealed vial.
Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.
Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.
Related reference materials
Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.
