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5-Amino-1MQ

$73.99

Lyophilized powder - research reference material

This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.

Quality Certificates

Independent third-party lab analysis (CoA) - from our own in-house brand.

5-Amino-1MQ - Selective NNMT Inhibitor Compound, Research Reference Material

FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.

2D chemical structure of 5-Amino-1MQ - Selective NNMT Inhibitor Compound, Research Reference Material
Two-dimensional chemical structure. Depiction for identification only.

Analytical Identity

Identity & nomenclature
Common name5-Amino-1MQ
CAS Number1034043-18-3
PubChem CID950107 (free base), 66522933 (iodide salt)
InChIKeyZMJBCEIHNOWCMC-UHFFFAOYSA-O
SMILESC[N+]1=CC=CC2=C(C=CC=C21)N
Physicochemical
Molecular formulaC10H11N2+ (free base), C10H11IN2 (iodide salt), C10H11ClN2 (chloride salt)
Molecular weight215.26 g/mol
Monoisotopic mass159.0922 Da
AppearanceWhite to off-white lyophilized powder
Physical formLyophilized powder
Quality & provenance
PurityNot less than 98% by HPLC (see lot-specific Certificate of Analysis)
SourceSynthetic
Catalog / SKU5-Amino-1MQ

5-Amino-1MQ is supplied as a laboratory research reference material intended strictly for in-vitro and other laboratory research use. The compound is a small-molecule quaternary quinolinium salt referenced in the published literature as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), studied in preclinical enzymology and cell-based assay systems.

Structurally, 5-Amino-1MQ (5-amino-1-methylquinolinium) consists of a quinoline scaffold bearing a primary amine at the 5-position and a permanent positive charge on the ring nitrogen introduced by N1-methylation. The cationic core corresponds to the free-base formula C10H11N2+ with a formula weight of 215.26 g/mol and CAS 1034043-18-3. Commonly encountered salt forms include the iodide (C10H11IN2) and chloride (C10H11ClN2); PubChem indexes the free base under CID 950107 and the iodide salt under CID 66522933. The canonical SMILES is C[N+]1=CC=CC2=C(C=CC=C21)N, the InChIKey is ZMJBCEIHNOWCMC-UHFFFAOYSA-O, and the monoisotopic mass of the cation is 159.0922 Da, providing convenient reference points for LC-MS confirmation and library matching.

Physical form is a white to off-white lyophilized powder produced by chemical synthesis, with purity of not less than 98% as determined by HPLC. The permanent quinolinium charge typically confers high aqueous solubility of the salt forms, making 5-Amino-1MQ convenient to reconstitute for analytical characterization workflows, orthogonal identity confirmation (HPLC-UV, LC-MS, NMR), and use as a chromatographic or spectroscopic reference standard alongside NNMT substrate/product analytes such as nicotinamide and 1-methylnicotinamide.

Published scientific literature has examined 5-Amino-1MQ in preclinical research contexts; PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. Lot-specific identity, purity, and counterion documentation are captured on the Certificate of Analysis, available on request.

Physical format

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Certificate of Analysis

Issuing laboratoryAnaliza Białek
Analyte5-Amino-1MQ
CAS Number1034043-18-3
Lot / BatchK12PP
AppearanceWhite to off-white lyophilized powder
Purity (HPLC)99%
IdentityConfirmed by HPLC and mass spectrometry

Lot-specific COA available — contact [email protected] with your lot number.

Storage & handling

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

Scientific references

The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.

  1. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice — https://pmc.ncbi.nlm.nih.gov/articles/PMC5826726/
  2. Roles of nicotinamide N-methyltransferase in obesity and type 2 diabetes mellitus — https://pmc.ncbi.nlm.nih.gov/articles/PMC8337113/

Eligibility & terms of sale

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.

FAQ

What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.

What form does it ship in?
A lyophilized powder in a sealed vial.

Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.

Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.

Related reference materials

Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.