CJC-1295 (No-DAC) + Ipamorelin

CJC-1295 (No-DAC) + Ipamorelin is supplied as a two-peptide laboratory research reference material intended strictly for in-vitro and laboratory investigation. The kit pairs a 30-mer tetrasubstituted growth-hormone-releasing hormone (GHRH) analog, CJC-1295 without the drug affinity complex (No-DAC), with a pentapeptide growth-hormone secretagogue, ipamorelin. The two components are provided as discrete lyophilized solids so that investigators can independently reconstitute, weigh, and combine them at ratios appropriate to their assay design.

The CJC-1295 (No-DAC) component (CAS 863288-34-0) is a synthetic analog of the N-terminal 1-29 fragment of human GHRH bearing four stabilizing substitutions (D-Ala at position 2, Gln at 8, Ala at 15, and Leu at 27) that reduce enzymatic cleavage by dipeptidyl peptidase-IV and endopeptidases relative to the native sequence. Its molecular formula is C152H252N44O42 with an average molecular weight of approximately 3367.9 g/mol, and its full sequence is Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Gln-Ala-His-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Gln-Ala-His-Asn-Ser-Tyr-Arg-Lys-Leu-Leu. Because this variant lacks the maleimidopropionyl "DAC" linker used to conjugate serum albumin, it presents a shorter analytical half-life profile than DAC-modified analogs, a distinction relevant to pharmacokinetic modeling and reference-standard selection.

The ipamorelin component (CAS 170851-70-4) is a C-terminally amidated pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2, molecular formula C38H49N9O5, and molecular weight 711.9 g/mol. It incorporates two non-proteinogenic residues, alpha-aminoisobutyric acid (Aib) and D-2-naphthylalanine (D-2-Nal), together with a D-Phe residue, features that support conformational rigidity and chromatographic identity confirmation. This structural class is commonly cited as a ghrelin/GHS-R1a receptor ligand in the published peptide chemistry literature, distinct in scaffold from GHRH analogs such as CJC-1295 (No-DAC).

Both peptides are synthetic in origin, produced by solid-phase peptide synthesis and purified to not less than 98% by reversed-phase HPLC, with identity confirmed by mass spectrometry. Each lot is accompanied by a Certificate of Analysis reporting HPLC purity, mass-spec identity, appearance, and net peptide content; the CoA is the definitive document for lot-specific characterization and is available on request. The physical form is a white to off-white lyophilized powder for each component, suitable for gravimetric handling and reconstitution in laboratory solvents compatible with downstream analytical workflows such as LC-MS, ELISA cross-reactivity panels, receptor-binding characterization, and stability studies.

Published scientific literature has examined CJC-1295 (No-DAC) and ipamorelin, individually and as a paired GHRH/GHRP research combination, in preclinical and in-vitro contexts. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding CJC-1295 (No-DAC) + Ipamorelin and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. It is offered exclusively to qualified researchers and institutions for laboratory reference and characterization purposes.

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.