MOTS-c
$88.99
This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.
Quality Certificates
Independent third-party lab analysis (CoA) - from our own in-house brand.
MOTS-c - Mitochondrial-Derived 16-Amino-Acid Peptide, Research Reference Material
FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.

Analytical Identity
| Common name | MOTS-c |
|---|---|
| Amino-acid sequence | MRWQEMGYIFYPRKLR |
| Sequence (3-letter) | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Residues | 16 |
| CAS Number | 1415585-49-1 |
| Molecular formula | C136H224N38O38 |
|---|---|
| Molecular weight | ~2172.6 g/mol |
| Appearance | White to off-white lyophilized powder |
| Physical form | Lyophilized powder |
| Purity | Not less than 98% by HPLC (see lot-specific Certificate of Analysis) |
|---|---|
| Source | Synthetic |
| Catalog / SKU | MOTS-c |
MOTS-c is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. The item is a synthetic 16-residue peptide corresponding to the sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (one-letter: MRWQEMGYIFYPRKLR), assigned CAS 1415585-49-1, with a molecular formula of C136H224N38O38 and a calculated monoisotopic-consistent average molecular weight of approximately 2172.6 g/mol.
From a compositional standpoint, MOTS-c contains a mixture of hydrophobic (Met, Trp, Ile, Phe, Leu, Tyr), basic (two Arg, one Lys), acidic (Glu), polar-uncharged (Gln, Tyr), and conformationally restrictive (Pro, Gly) residues, giving the sequence a net positive charge at neutral pH. The presence of two internal methionines and one tryptophan makes the material a useful reference for studying oxidation-sensitive residues during handling and analytical workups, while the paired tyrosines and single tryptophan provide characteristic UV absorbance around 274-280 nm that is convenient for spectrophotometric identity checks and concentration estimation in research settings.
Physically, MOTS-c is provided as a white to off-white lyophilized powder produced by chemical synthesis (solid-phase peptide synthesis workflows), with purity of not less than 98% as determined by reversed-phase HPLC. Identity is typically confirmed by mass spectrometry consistent with the C136H224N38O38 composition, and both identity and purity values are documented on the lot-specific Certificate of Analysis, available on request. The lyophilized format supports reconstitution in laboratory solvents chosen by the investigator for their specific analytical, chromatographic, or reference-standard application.
Published scientific literature has examined MOTS-c in preclinical, cell-based, and biochemical research contexts, and its mitochondrial-derived 16-amino-acid peptide profile has made it a recurring subject of characterization studies. PEPTIDE.Power provides this material strictly as a chemical reference standard and makes no therapeutic, diagnostic, or efficacy claims regarding MOTS-c, nor any administration, dosing, formulation, or handling guidance for living subjects. This material is not a drug, dietary supplement, cosmetic, or food ingredient, and it is not intended for human or veterinary use, injection, ingestion, topical application, or any in-vivo purpose.
Physical format
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.
Certificate of Analysis
| Issuing laboratory | Analiza Białek |
|---|---|
| Analyte | MOTS-c |
| CAS Number | 1415585-49-1 |
| Lot / Batch | K12PP |
| Appearance | White to off-white lyophilized powder |
| Purity (HPLC) | 99% |
| Identity | Confirmed by HPLC and mass spectrometry |
Lot-specific COA available — contact [email protected] with your lot number.
Storage & handling
Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.
Scientific references
The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.
- Mitochondria-derived peptide MOTS-c restores mitochondrial ... — https://pmc.ncbi.nlm.nih.gov/articles/PMC12257629/
Eligibility & terms of sale
This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.
FAQ
What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.
What form does it ship in?
A lyophilized powder in a sealed vial.
Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.
Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.
Related reference materials
Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.
