Glutathione
$70.99
Supplied solely as a dietary reference material. Buyer is responsible for lawful, compliant handling and use. We do not provide administration, dosing, or therapeutic guidance.
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Analytical Identity
| Common name | Glutathione |
|---|---|
| Amino-acid sequence | H-γ-Glu-Cys-Gly-OH |
| CAS Number | 70-18-8 |
| PubChem CID | 124886 |
| InChIKey | RWSXRVCMGQZWBV-WDSKDSINSA-N |
| SMILES | C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N |
| Molecular formula | C10H17N3O6S |
|---|---|
| Molecular weight | 307.32 g/mol |
| Monoisotopic mass | 307.0838 Da |
| Appearance | White to off-white lyophilized powder |
| Physical form | Lyophilized powder |
| Purity | Not less than 98% by HPLC (see lot-specific Certificate of Analysis) |
|---|---|
| Source | Synthetic |
| Catalog / SKU | Glutathione |
Glutathione (CAS 70-18-8) is offered as a laboratory reference material for analytical, characterization and method-development workflows. It is not a drug, dietary supplement, cosmetic or food, and is not intended for human or veterinary use, injection or ingestion.
Structurally, Glutathione is the endogenous tripeptide H-γ-Glu-Cys-Gly-OH, in which the N-terminal glutamate is linked to cysteine through its gamma-carboxyl rather than the standard alpha-carboxyl. This isopeptide bond is the defining topological feature of the molecule and is a common reference point in peptide-bond regiochemistry and mass-spectral fragmentation studies. The central cysteine contributes a free thiol (-SH), which underlies the compound's utility as a redox and derivatization standard in HPLC, LC-MS and CE assays.
The material is characterized by molecular formula C10H17N3O6S, average molecular weight 307.32 g/mol and monoisotopic mass 307.0838 Da, with PubChem CID 124886, InChIKey RWSXRVCMGQZWBV-WDSKDSINSA-N and canonical SMILES C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N. The stereochemistry encoded in the InChIKey reflects the L,L-configuration of the constituent amino acids, and the [M+H]+ ion at m/z 308.09 and [M-H]- at m/z 306.08 are useful reference signals for tuning and system-suitability checks.
Supplied as a synthetic, white to off-white lyophilized powder, Glutathione is packaged for use as a reference material and specified at not less than 98% purity by HPLC, with identity and purity documented on the lot-specific Certificate of Analysis, available on request. Analytical release testing typically pairs reversed-phase HPLC with orthogonal confirmation by mass spectrometry against the theoretical monoisotopic mass.
Formulators and analysts working with this Glutathione reference item should note that the free thiol is oxidation-sensitive and will slowly form the corresponding disulfide (GSSG) on exposure to air, moisture or trace metal ions; storage of the lyophilized solid cold, dry and protected from light, and preparation of working solutions in degassed, slightly acidic aqueous media, help preserve the reduced form during characterization work.
These statements have not been evaluated by the Food and Drug Administration; this material is not intended to diagnose, treat, cure or prevent any disease.
Physical format
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.
Certificate of Analysis
| Analyte | Glutathione |
|---|---|
| CAS Number | 70-18-8 |
| Appearance | White to off-white lyophilized powder |
| Identity | Confirmed by HPLC and mass spectrometry |
Lot-specific COA available — contact [email protected] with your lot number.
Storage & handling
Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.
Scientific references
The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.
- Randomized controlled trial of oral glutathione supplementation on body stores of glutathione — https://pubmed.ncbi.nlm.nih.gov/24791752/
- Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function — https://pubmed.ncbi.nlm.nih.gov/28853742/
- Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression — https://pubmed.ncbi.nlm.nih.gov/39012509/
- Glutathione system enhancement for cardiac protection: pharmacological and clinical data from bench-to-bedside — https://pubmed.ncbi.nlm.nih.gov/36792953/
- Randomized clinical trial of how long-term glutathione supplementation improves lipid metabolism in obese patients with nonalcoholic fatty liver disease — https://pubmed.ncbi.nlm.nih.gov/35631350/
- ALSUntangled no. 52: glutathione — https://pubmed.ncbi.nlm.nih.gov/31797650/
Eligibility & terms of sale
This material is sold as a dietary reference material for lawful use only. By purchasing, you confirm you are 21 or older and will handle and use it in compliance with all applicable laws. These statements have not been evaluated by the Food and Drug Administration.
FAQ
What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.
What form does it ship in?
A lyophilized powder in a sealed vial.
Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.
Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.
Related reference materials
Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
