CJC 1295 (with DAC)

CJC-1295 (with DAC) is supplied by PEPTIDE.Power as a laboratory research reference material for in-vitro and laboratory research use only. This synthetic 29-residue peptide corresponds to the N-terminal active fragment of growth hormone releasing hormone, GHRH(1-29), extended with a Drug Affinity Complex (DAC) modification: an N-epsilon-3-maleimidopropionamide lysine residue that enables covalent conjugation to circulating serum albumin via Michael addition to the free cysteine-34 thiol. The peptide is further stabilized by targeted amino-acid substitutions within the GHRH(1-29) template (D-Ala at position 2, Gln at 8, Ala at 15, and Leu at 27) that reduce susceptibility to enzymatic cleavage relative to the native sequence.

The verified identity of the material is captured by CAS Number 863288-34-0, PubChem CID 91971820, molecular formula C165H269N47O46, and a monoisotopic-consistent average molecular weight of 3647.2 g/mol. The full primary structure is YADAIFTQSYRKVLAQLSARKLLQDIMSR, with the DAC linker appended at the C-terminal lysine side chain and the C-terminus presented as the amide. CJC-1295 (with DAC) is produced by chemical synthesis and isolated as a white to off-white lyophilized powder.

Each lot of CJC-1295 (with DAC) is characterized by reversed-phase HPLC to establish a purity specification of not less than 98%, with orthogonal confirmation of identity by mass spectrometry against the theoretical mass derived from C165H269N47O46. Lot-specific data including chromatographic purity, mass confirmation, appearance, and residual-solvent or water content, where applicable, are documented on the Certificate of Analysis available on request under catalog SKU CJC-1295-DAC. Analytically, the DAC maleimide handle makes the molecule a useful reference standard for in-vitro albumin-conjugation studies, LC-MS method development, and comparative characterization of GHRH-analog peptides in bench-scale research.

Published scientific literature has examined CJC-1295 (with DAC) in preclinical research contexts, and PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance of any kind. CJC-1295 (with DAC) is not a drug, dietary supplement, cosmetic, or food, and is not intended or suitable for human or veterinary use, injection, or ingestion; it is offered exclusively as an analytical and laboratory reference material for qualified researchers.

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.