Semax

$74.99

Lyophilized powder - research reference material

This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.

Quality Certificates

Independent third-party lab analysis (CoA) - from our own in-house brand.

Semax - Synthetic ACTH-Derived Heptapeptide, Research Reference Material

FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.

2D chemical structure of Semax - Synthetic ACTH-Derived Heptapeptide, Research Reference Material
Two-dimensional chemical structure. Depiction for identification only.
Amino-acid sequence of Semax - Synthetic ACTH-Derived Heptapeptide, Research Reference Material
Primary amino-acid sequence, N to C. Tiles colored by side-chain class.

Analytical Identity

Identity & nomenclature
Common nameSemax
Amino-acid sequenceMEHFPGP
Sequence (3-letter)Met-Glu-His-Phe-Pro-Gly-Pro
Residues7
CAS Number80714-61-0
PubChem CID9811102
InChIKeyAFEHBIGDWIGTEH-AQRCPPRCSA-N
SMILESCSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)N3CCCC3C(=O)NCC(=O)N4CCCC4C(=O)O)N
Physicochemical
Molecular formulaC37H51N9O10S
Molecular weight813.9 g/mol
Monoisotopic mass813.3480 Da
AppearanceWhite to off-white lyophilized powder
Physical formLyophilized powder
Quality & provenance
PurityNot less than 98% by HPLC (see lot-specific Certificate of Analysis)
SourceSynthetic
Catalog / SKUSemax

Semax is supplied as a laboratory research reference material intended strictly for in-vitro and laboratory research use only. This synthetic heptapeptide is a structural analog derived from a fragment of adrenocorticotropic hormone (ACTH 4-10), extended at the C-terminus with a Pro-Gly-Pro tripeptide motif that alters its physicochemical profile relative to the parent ACTH sequence. The linear seven-residue sequence is MEHFPGP (Met-Glu-His-Phe-Pro-Gly-Pro), incorporating a sulfur-containing methionine at the N-terminus, an acidic glutamate, an imidazole-bearing histidine, an aromatic phenylalanine, and two proline residues flanking a central glycine.

The Semax reference material is characterized by the molecular formula C37H51N9O10S, an average molecular weight of 813.9 g/mol, and a monoisotopic mass of 813.3480 Da, corresponding to CAS 80714-61-0 and PubChem CID 9811102. Stereochemistry and connectivity are captured by InChIKey AFEHBIGDWIGTEH-AQRCPPRCSA-N and the canonical SMILES string CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)N3CCCC3C(=O)NCC(=O)N4CCCC4C(=O)O)N, providing unambiguous identifiers for cross-referencing in analytical databases and cheminformatics workflows.

Each lot of Semax is produced by chemical synthesis and presents as a white to off-white lyophilized powder. Purity is not less than 98% as determined by HPLC, with identity, purity, mass confirmation and residual profile documented on the lot-specific Certificate of Analysis available on request. The methionine thioether and histidine imidazole are known handles that formulators typically consider when planning solvent compatibility, buffer selection, and long-term storage studies of research peptides of this class.

Published scientific literature has examined Semax in preclinical and in-vitro research contexts, and the identifiers above allow investigators to align in-house analytical data with peer-reviewed reports. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion.

Physical format

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Certificate of Analysis

Issuing laboratoryAnaliza Białek
AnalyteSemax
CAS Number80714-61-0
Lot / BatchK12PP
AppearanceWhite to off-white lyophilized powder
Purity (HPLC)99%
IdentityConfirmed by HPLC and mass spectrometry

Lot-specific COA available — contact [email protected] with your lot number.

Storage & handling

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

Scientific references

The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.

  1. Semax, an analogue of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus — https://pubmed.ncbi.nlm.nih.gov/18537808/
  2. Semax, an analog of ACTH(4-7), regulates expression of immune response genes during ischemic brain injury in rats — https://pubmed.ncbi.nlm.nih.gov/21520481/
  3. Heptapeptide Semax Effects on Expression of Genes Related to Neurotransmitter Systems — https://pmc.ncbi.nlm.nih.gov/articles/PMC5650345/
  4. Heptapeptide semax attenuates the effects of chronic unpredictable stress in rats — https://pubmed.ncbi.nlm.nih.gov/17117973/
  5. The nootropic and analgesic effects of Semax following different routes of administration — https://pubmed.ncbi.nlm.nih.gov/9333452/
  6. Semax, an analog of ACTH(4-7), regulates expression of immune response genes in ischemic rat brain — https://pmc.ncbi.nlm.nih.gov/articles/PMC4133108/

Eligibility & terms of sale

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.

FAQ

What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.

What form does it ship in?
A lyophilized powder in a sealed vial.

Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.

Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.

Related reference materials

Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.