Tesofensin Capsules

Price range: $80.99 through $134.99

Encapsulated research material - research reference material

This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.

Tesofensin - Synthetic Monoamine Reuptake Inhibitor, Research Reference Material

FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.

2D chemical structure of Tesofensin - Synthetic Monoamine Reuptake Inhibitor, Research Reference Material
Two-dimensional chemical structure. Depiction for identification only.

Analytical Identity

Identity & nomenclature
Common nameTesofensin
CAS Number402856-42-2
PubChem CID11370864
InChIKeyVCVWXKKWDOJNIT-ZOMKSWQUSA-N
SMILESCCOCC1C2CCC(N2C)CC1C3=CC(=C(C=C3)Cl)Cl
Physicochemical
Molecular formulaC17H23Cl2NO
Molecular weight328.28 g/mol
Monoisotopic mass327.1157 Da
AppearanceEncapsulated powder
Physical formCapsules
Quality & provenance
PurityNot less than 98% by HPLC (see lot-specific Certificate of Analysis)
SourceSynthetic
Catalog / SKUTESOFENSIN

Tesofensin (CAS 402856-42-2) is supplied as a synthetic laboratory research reference material intended solely for in-vitro and other non-clinical laboratory investigations. The material is offered under catalog identifier TESOFENSIN in an encapsulated powder format, packaged to support gravimetric handling, reconstitution studies, and analytical method development workflows in a controlled laboratory environment.

From a structural chemistry standpoint, Tesofensin is a small-molecule tropane derivative with the molecular formula C17H23Cl2NO and a calculated molecular weight of 328.28 g/mol, with a monoisotopic mass of 327.1157 Da. Its canonical SMILES string CCOCC1C2CCC(N2C)CC1C3=CC(=C(C=C3)Cl)Cl encodes an N-methyl-8-azabicyclo[3.2.1]octane (tropane) core bearing an ethoxymethyl substituent and a 3,4-dichlorophenyl group, features that define its identity and chromatographic behavior. The stereochemistry is captured by InChIKey VCVWXKKWDOJNIT-ZOMKSWQUSA-N, and additional descriptor data can be cross-referenced through PubChem CID 11370864 for method setup, spectral library matching, and cheminformatics comparison.

Each lot of Tesofensin is released against specifications of not less than 98% purity as determined by HPLC, with identity and purity metrics documented on a lot-specific Certificate of Analysis available on request. The dichlorophenyl chromophore lends itself to UV detection at typical analytical wavelengths, and the tertiary amine along with the ether linkage make the compound amenable to LC-MS and reversed-phase separations commonly used in reference-material characterization.

Published scientific literature has examined Tesofensin as a monoamine reuptake inhibitor in preclinical research contexts, and it is offered here strictly as a chemical reference article to support such analytical, comparative, and physicochemical studies. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not intended for human or veterinary use, injection, or ingestion.

Physical format

Supplied as encapsulated research material in a sealed container. A research reference material - not a finished product. Net contents per unit are shown in the product options.

Certificate of Analysis

AnalyteTesofensin
CAS Number402856-42-2
AppearanceEncapsulated powder
IdentityConfirmed by HPLC and mass spectrometry

Lot-specific COA available — contact [email protected] with your lot number.

Storage & handling

Store the sealed container at room temperature, protected from light, heat, and moisture. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

Scientific references

The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.

  1. Astrup A, Madsbad S, et al. Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial. Lancet. 2008. — https://pubmed.ncbi.nlm.nih.gov/18950853/
  2. Axel AM, Mikkelsen JD, Hansen HH. Tesofensine, a novel triple monoamine reuptake inhibitor, induces appetite suppression by indirect stimulation of alpha1 adrenoceptor and dopamine D1 receptor pathways in the diet-induced obese rat. Neuropsychopharmacology. 2010. — https://pubmed.ncbi.nlm.nih.gov/20200509/
  3. Appel L, Bergström M, et al. Tesofensine, a novel triple monoamine re-uptake inhibitor with anti-obesity effects: dopamine transporter occupancy as measured by PET. Eur Neuropsychopharmacol. 2014. — https://pubmed.ncbi.nlm.nih.gov/24239329/
  4. Gilbert JA, Gasteyger C, et al. The effect of tesofensine on appetite sensations. Obesity (Silver Spring). 2012. — https://pubmed.ncbi.nlm.nih.gov/21720440/
  5. Bello NT, Zahner MR. Tesofensine, a monoamine reuptake inhibitor for the treatment of obesity. Curr Opin Investig Drugs. 2009. — https://pubmed.ncbi.nlm.nih.gov/19777399/

Eligibility & terms of sale

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.

FAQ

What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.

What form does it ship in?
Encapsulated research material in a sealed container.

Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.

Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.

Related reference materials

Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.