Epithalon

$69.99

Lyophilized powder - research reference material

This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.

Quality Certificates

Independent third-party lab analysis (CoA) - from our own in-house brand.

Epithalon - Synthetic Tetrapeptide, Research Reference Material

FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.

2D chemical structure of Epithalon - Synthetic Tetrapeptide, Research Reference Material
Two-dimensional chemical structure. Depiction for identification only.
Amino-acid sequence of Epithalon - Synthetic Tetrapeptide, Research Reference Material
Primary amino-acid sequence, N to C. Tiles colored by side-chain class.

Analytical Identity

Identity & nomenclature
Common nameEpithalon
Amino-acid sequenceAEDG
Sequence (3-letter)Ala-Glu-Asp-Gly
Residues4
CAS Number307297-39-8
PubChem CID219042
InChIKeyHGHOBRRUMWJWCU-FXQIFTODSA-N
SMILESCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NCC(=O)O)N
Physicochemical
Molecular formulaC14H22N4O9
Molecular weight390.35 g/mol
Monoisotopic mass390.1387 Da
AppearanceWhite to off-white lyophilized powder
Physical formLyophilized powder
Quality & provenance
PurityNot less than 98% by HPLC (see lot-specific Certificate of Analysis)
SourceSynthetic
Catalog / SKUEpithalon

Epithalon is supplied as a laboratory research reference material for in-vitro and laboratory research use only. It is a fully synthetic linear tetrapeptide composed of four residues (Ala-Glu-Asp-Gly, one-letter AEDG), presenting a free N-terminal alanine amine and a C-terminal glycine carboxylate, with two additional pendant carboxylic acid groups contributed by the internal glutamic and aspartic acid side chains. This acidic side-chain profile gives Epithalon a low isoelectric point and strong aqueous solubility in neutral to mildly basic buffers, a property useful when preparing stock solutions for analytical characterization work.

Identity is defined by molecular formula C14H22N4O9, monoisotopic mass 390.1387 Da, average molecular weight 390.35 g/mol, and CAS 307297-39-8, cross-referenced to PubChem CID 219042 and InChIKey HGHOBRRUMWJWCU-FXQIFTODSA-N. The canonical SMILES CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NCC(=O)O)N encodes the L-configured Ala-Glu-Asp-Gly backbone with three amide bonds linking the four residues. The material is produced by chemical synthesis and supplied as a white to off-white lyophilized powder at not less than 98% purity by HPLC, with lot-specific identity, purity, and residual profile documented on the Certificate of Analysis available on request.

Published scientific literature has examined Epithalon in preclinical research contexts, and it is frequently referenced by investigators evaluating short acidic peptides, HPLC method development, mass spectrometric identification workflows (expected [M+H]+ near 391.15), and comparative stability studies of small oligopeptides bearing multiple carboxylate functionalities. Because of the two free carboxylic acids and the free primary amine, Epithalon is a useful reference standard for reversed-phase separations, ion-pair chromatography, and calibration of low-molecular-weight peptide assays.

For storage and handling in the laboratory, the lyophilized powder is typically kept sealed, protected from moisture and light, and reconstituted only in analytically appropriate solvents at the time of use to preserve chromatographic integrity. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding Epithalon and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion; it is intended solely as a laboratory reference substance for qualified research personnel working in a controlled research setting.

Physical format

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Certificate of Analysis

Issuing laboratoryAnaliza Białek
AnalyteEpithalon
CAS Number307297-39-8
Lot / BatchK12PP
AppearanceWhite to off-white lyophilized powder
Purity (HPLC)99%
IdentityConfirmed by HPLC and mass spectrometry

Lot-specific COA available — contact [email protected] with your lot number.

Storage & handling

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

Scientific references

The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.

  1. Peptide promotes overcoming of the division limit in human somatic cell — https://pubmed.ncbi.nlm.nih.gov/12937682/
  2. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells — https://pubmed.ncbi.nlm.nih.gov/14523363/
  3. Inhibition of development of spontaneous mammary tumors in mice by Epithalon — https://pubmed.ncbi.nlm.nih.gov/17415625/
  4. Effect of Epithalon on biomarkers of aging, life span and spontaneous tumor incidence in female rats — https://pubmed.ncbi.nlm.nih.gov/12937674/
  5. Pineal peptide preparation Epithalamin and tetrapeptide Epitalon: results of clinical use in humans — https://pubmed.ncbi.nlm.nih.gov/15622723/
  6. Peptides and aging: relevance to cancer prevention and longevity research — https://pmc.ncbi.nlm.nih.gov/articles/PMC4523074/

Eligibility & terms of sale

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.

FAQ

What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.

What form does it ship in?
A lyophilized powder in a sealed vial.

Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.

Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.

Related reference materials

Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.