Sermorelin

Sermorelin is supplied as a laboratory research reference material for in-vitro and laboratory research use only. It is a fully synthetic 29-residue peptide corresponding to the N-terminal fragment of the human growth hormone-releasing hormone family, presented here strictly as a characterized reference standard for analytical, comparative, and method-development workflows.

The material is defined by the molecular formula C149H246N44O42S, an average molecular weight of 3357.9 g/mol, and a monoisotopic mass of 3355.8187 Da. It is registered under CAS 86168-78-7 and PubChem CID 16129620, with InChIKey WGWPRVFKDLAUQJ-UHFFFAOYSA-N for unambiguous cross-referencing in cheminformatics databases and electronic laboratory notebooks. The single sulfur atom in the formula reflects the lone methionine residue at position 27, a feature relevant to oxidation-state monitoring during long-term storage and stability studies.

The primary structure is YADAIFTNSYRKVLGQLSARKLLQDIMSR (Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg), 29 residues in length, with a free N-terminal tyrosine and a C-terminal arginine. The sequence contains three arginines and two lysines, contributing to a net-basic character at physiological pH, alongside two aspartate residues, one methionine, and multiple hydroxyl-bearing residues (tyrosine, threonine, serine) that inform reversed-phase retention behavior and pI estimation during analytical characterization of Sermorelin reference lots.

Physical form is a white to off-white lyophilized powder produced by synthetic solid-phase peptide synthesis, with purity of not less than 98% as determined by HPLC. Identity is confirmed by mass spectrometry against the calculated monoisotopic mass, and sequence composition is consistent with the SMILES and formula records above. These attributes make Sermorelin suitable as a reference standard for HPLC retention-time matching, UV response calibration at 214 and 280 nm (leveraging the two tyrosine chromophores), LC-MS peak identification, and orthogonal purity assessment.

Published scientific literature has examined Sermorelin in preclinical research; PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance. Investigators are encouraged to consult primary literature and to design their own analytical protocols, using this lyophilized reference material for method qualification, standard-curve preparation, impurity profiling, and comparative structural studies.

This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. Identity and purity are documented on the lot-specific Certificate of Analysis, available on request, which reports HPLC purity, mass-spectrometric identity confirmation, appearance, and net peptide content for the specific Sermorelin lot supplied.

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.