SS-31

SS-31 is supplied as a laboratory research reference material for in-vitro and laboratory research use only. This synthetic tetrapeptide is characterized by the molecular formula C32H49N9O5, a molecular weight of 639.8 g/mol, and a monoisotopic mass of 639.3857 Da, corresponding to CAS registry number 736992-21-5 and PubChem CID 11764719. The primary structure is defined by the amino-acid sequence D-Arg-Dmt-Lys-Phe-NH2, an alternating aromatic-cationic motif built on a D-arginine N-terminus, a 2',6'-dimethyltyrosine (Dmt) residue, an L-lysine, and a C-terminal L-phenylalanine amide.

The stereochemistry and connectivity of SS-31 are captured by the InChIKey SFVLTCAESLKEHH-WKAQUBQDSA-N and the isomeric SMILES CC1=CC(=CC(=C1CC(C(=O)NC(CCCCN)C(=O)NC(CC2=CC=CC=C2)C(=O)N)NC(=O)C(CCCN=C(N)N)N)C)O. The presence of a D-configured arginine at position 1 and the sterically hindered Dmt residue distinguish SS-31 from linear all-L tetrapeptides and are useful reference points during LC-MS, NMR, and chiral HPLC characterization. The C-terminal primary amide and the two basic side chains (guanidinium of Arg, epsilon-amine of Lys) give the molecule a net positive charge under typical aqueous buffer conditions, a property relevant to reversed-phase retention behavior, ion-pairing method development, and counter-ion selection in analytical workflows.

Material is provided as a white to off-white lyophilized powder of synthetic origin, catalog SKU SS-31, with purity not less than 98% by HPLC. Identity and purity for each production lot are documented on the lot-specific Certificate of Analysis, available on request, and typically include HPLC purity, mass confirmation consistent with 639.8 g/mol, appearance, and residual-content parameters suitable for use as a characterization standard, reference peak marker, or comparator in method qualification and stability-indicating assay development.

Published scientific literature has examined SS-31 in preclinical research, and its well-defined structural signature makes it a convenient benchmark peptide for investigators developing analytical methods around aromatic-cationic tetrapeptides and Dmt-containing sequences. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion.

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.