AICAR

AICAR is supplied as a laboratory research reference material intended strictly for in-vitro and laboratory research use only. This lot is furnished as a white to off-white lyophilized powder of synthetic origin, packaged for analytical benchtop workflows such as HPLC method development, LC-MS calibration, NMR structural confirmation, and use as a chromatographic reference standard.

AICAR (CAS 2627-69-2, PubChem CID 65110) is characterized by the molecular formula C9H14N4O8P and a molecular weight of 338.21 g/mol, with a monoisotopic mass of 338.0628 Da suitable for high-resolution mass spectrometry confirmation. Structurally, AICAR is an AMP nucleotide analog consisting of a 5-aminoimidazole-4-carboxamide heterocycle N-glycosidically linked to a beta-D-ribofuranose bearing a 5'-monophosphate group, as encoded in the SMILES string C1=NC(=C(N1C2C(C(C(O2)COP(=O)(O)O)O)O)N)C(=O)N and the stereodescriptive InChIKey NOTGFIUVDGNKRI-UUOKFMHZSA-N. The molecule presents three ionizable centers relevant to method development, namely the phosphate diprotic system, the exocyclic amine, and the imidazole nitrogen, which together govern retention behavior on reversed-phase, ion-pair, and HILIC stationary phases.

Analytical identity and chromatographic purity are established at not less than 98% by HPLC, with lot-specific values, residual solvent notes, and orthogonal identity data recorded on the Certificate of Analysis available on request. Formulators and analytical chemists commonly reconstitute AICAR reference material in aqueous buffers appropriate to the pKa profile of the phosphate and imidazole functionalities; the lyophilized format supports extended cold, desiccated storage and accurate gravimetric preparation of stock solutions for calibration curves.

Published scientific literature has examined AICAR in preclinical and mechanistic research contexts, and it is frequently cited as a purine biosynthesis pathway intermediate analog in in-vitro biochemistry investigations. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding this material and provides no administration or dosing guidance. This material is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion.

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.