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Thymosin alpha 1

$103.99

Lyophilized powder - research reference material

This material is supplied solely as a laboratory research article. Buyer is responsible for ensuring lawful purchase, handling, storage, and use. We do not provide administration or therapeutic guidance.

Quality Certificates

Independent third-party lab analysis (CoA) - from our own in-house brand.

Thymosin Alpha 1 - Synthetic Thymic Peptide, Research Reference Material

FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.

2D chemical structure of Thymosin Alpha 1 - Synthetic Thymic Peptide, Research Reference Material
Two-dimensional chemical structure. Depiction for identification only.
Amino-acid sequence of Thymosin Alpha 1 - Synthetic Thymic Peptide, Research Reference Material
Primary amino-acid sequence, N to C. Tiles colored by side-chain class.

Analytical Identity

Identity & nomenclature
Common nameThymosin Alpha 1
Amino-acid sequenceSDAAVDTSSEITTKDLKEKKEVVEEAEN
Sequence (3-letter)Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn
Residues28
CAS Number62304-98-7
PubChem CID16130571
InChIKeyNZVYCXVTEHPMHE-ZSUJOUNUSA-N
SMILESCCC(C)C(C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC(=O)O)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C
Physicochemical
Molecular formulaC129H215N33O55
Molecular weight3108.3 g/mol
Monoisotopic mass3106.5041 Da
AppearanceWhite to off-white lyophilized powder
Physical formLyophilized powder
Quality & provenance
PurityNot less than 98% by HPLC (see lot-specific Certificate of Analysis)
SourceSynthetic
Catalog / SKUThymosin-alpha-1

Thymosin Alpha 1 is supplied as a laboratory research reference material intended solely for in-vitro and laboratory research use. This synthetic 28-residue acetylated N-terminal fragment of prothymosin is offered under catalog SKU Thymosin-alpha-1 as a white to off-white lyophilized powder, produced by solid-phase peptide synthesis and characterized to support identity, purity, and structural confirmation workflows in analytical chemistry, peptide reference standardization, and comparative binding or receptor-interaction studies conducted in vitro.

The material is defined by the molecular formula C129H215N33O55, an average molecular weight of 3108.3 g/mol, and a monoisotopic mass of 3106.5041 Da, with CAS Number 62304-98-7 and PubChem CID 16130571. The primary structure corresponds to the amino-acid sequence SDAAVDTSSEITTKDLKEKKEVVEEAEN (Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn), a highly acidic sequence rich in glutamic and aspartic acid residues that renders Thymosin Alpha 1 a strongly polar, water-soluble peptide with a low isoelectric point. The InChIKey NZVYCXVTEHPMHE-ZSUJOUNUSA-N supports unambiguous cheminformatic lookup and cross-referencing against public structural databases.

For analytical characterization, Thymosin Alpha 1 is suitable as a reference standard in reversed-phase HPLC identity and purity assays, ESI and MALDI mass spectrometry (where the monoisotopic mass of 3106.5041 Da and the average mass of 3108.3 g/mol serve as orthogonal confirmation points), amino-acid analysis, Edman sequencing, and circular dichroism studies of short acidic peptides. Purity is specified as not less than 98% by HPLC, with lot-specific values, residual solvent notes, counter-ion content, and water content reported on the Certificate of Analysis accompanying each batch.

Published scientific literature has examined Thymosin Alpha 1 in preclinical and in-vitro research contexts, and this listing is provided strictly to describe the physicochemical and analytical properties of the reference material. PEPTIDE.Power makes no therapeutic, diagnostic, or efficacy claims regarding Thymosin Alpha 1 and provides no administration or dosing guidance of any kind. This material is not a drug, dietary supplement, cosmetic, or food; it is not intended for human or veterinary use, and is not intended for injection or ingestion. Identity and purity are documented on the lot-specific Certificate of Analysis, available on request to qualified research and institutional customers.

Physical format

Supplied as a lyophilized (freeze-dried) powder in a sealed vial. A research reference material - not a finished product and not a delivery device. Net contents per unit are shown in the product options.

Certificate of Analysis

Issuing laboratoryAnaliza Białek
AnalyteThymosin Alpha 1
CAS Number62304-98-7
Lot / BatchK12PP
AppearanceWhite to off-white lyophilized powder
Purity (HPLC)99%
IdentityConfirmed by HPLC and mass spectrometry

Lot-specific COA available — contact [email protected] with your lot number.

Storage & handling

Store the sealed lyophilized powder at -20 C, protected from light and moisture. After reconstitution for laboratory use, keep cold and use promptly. Handle per standard laboratory practice; a Safety Data Sheet (SDS) is available on request.

Scientific references

The following are independent, peer-reviewed publications provided for reference. They describe third-party research and are not representations by POWER BIOTECH LLC regarding this product.

  1. Thymosin alpha 1: A comprehensive review of the literature — https://pubmed.ncbi.nlm.nih.gov/29399790/
  2. Thymosin alpha 1 and cancer: action on immune effector and tumor target cells — https://pmc.ncbi.nlm.nih.gov/articles/PMC7102663/
  3. Thymosin alpha 1: a peptide immune modulator with a broad range of clinical applications — https://pubmed.ncbi.nlm.nih.gov/22650265/
  4. Thymosin alpha 1 reduces the mortality of severe COVID-19 by restoration of lymphocytopenia and reversion of exhausted T cells — https://pmc.ncbi.nlm.nih.gov/articles/PMC7833251/
  5. Thymosin alpha 1 represents a potential potent single-molecule-based therapy for cystic fibrosis — https://pubmed.ncbi.nlm.nih.gov/20697075/
  6. Thymosin alpha 1 activates dendritic cell tumor antigen processing and cross-presentation — https://pmc.ncbi.nlm.nih.gov/articles/PMC3535426/

Eligibility & terms of sale

This material is sold to qualified laboratory and research buyers for lawful research use only. It is not a drug, supplement, cosmetic, or food, and is not for human or veterinary use, injection, or ingestion. By purchasing, you confirm you are 21 or older and will use this material only for lawful laboratory research.

FAQ

What is the purity and how is it verified?
Not less than 98% by HPLC; see the Certificate of Analysis for the lot-specific result.

What form does it ship in?
A lyophilized powder in a sealed vial.

Can you advise on dosing, reconstitution, or administration?
No. We provide batch documentation, storage, and handling information only; we do not provide dosing, reconstitution, administration, or therapeutic guidance.

Is lot-specific documentation available?
Yes - contact [email protected] with your lot number for the Certificate of Analysis.

Related reference materials

Sold by POWER BIOTECH LLC, Casper, WY 82609, United States · [email protected]. FOR LABORATORY RESEARCH USE ONLY. Not a drug, supplement, cosmetic, or food. Not for human or veterinary use, ingestion, injection, or any in-vivo administration. Not evaluated by the FDA.